Both Gabriel Magalhaes and Jakub Kiwior were missing from their final training session before Sunday’s Premier League home game against Aston Villa.
The Gunners will go into the game sitting in second place on the table, following Manchester City’s 5-1 demolition of Luton Town on Saturday.
But Mikel Arteta’s men have the chance to reclaim top spot with victory over Villa.
However, Arteta appears to face two defensive injury headaches for the game against Unai Emery’s side.
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Gabriel, who has been nursing an Achilles issue over the last month, was absent from the training session on Friday and was not seen with his team-mates for their final preparations at the Emirates Stadium on Saturday.
Kiwior, who was taken off at halftime in the 2-2 draw with Bayern Munich in the Champions League on Tuesday evening, was also missing.
Takehiro Tomiyasu trained and could deputise at centre-back in Gabriel’s absence, while Oleksandr Zinchenko, who replaced Kiwior in the draw against Bayern, is also available.
